Side Effects of Saffron Supplementation

Saffron is considered a safe supplement to add to your daily regimen. Although side effects are rarely seen with saffron supplementation, some minor discomfort may occur, including

  1. Dry mouth
  2. Anxiety
  3. Dizziness/drowsiness
  4. Nausea
  5. Change in appetite
  6. A headache
Some people may exhibit allergic reactions to the carotenoids found in saffron. These reactions usually take form as hives, nasal congestion, or difficulty breathing Pregnant women should not take saffron (unless they consult a doctor), regardless of the potential benefits that have been demonstrated in earlier studies. Enough evidence indicates that saffron may pose a risk to the fetus and the mother Taking high doses of saffron for a long period of time may lower your red blood cell count

Drug Interactions

There are no known drug interactions with saffron supplements. However, this does not mean that supplementing with saffron while taking medications is safe. Saffron is presumed to have activity at the serotonin reuptake pump, acting as an inhibitor of this protein (SSRI). If you are taking an antidepressant that increases serotonin levels, consult your doctor before supplementing with saffron. You may be at risk of developing serotonin syndrome, which is a life-threatening condition.